Otogenetics helps clinicians in discovery of a novel autosomal dominant hearing loss mutation

Otogenetics hearing loss gene test lend the tool for clinicians to discover an autosomal dominant hearing loss mutation in POU4F3 gene. This particular variant t cosegregated with hearing loss in family members but was not detected in 580 normal hearing people. The mutation causes postlingual autosomal dominant nonsyndromic hearing loss that is progressive and characterized with an unusual midfrequency hearing loss.

Learn More