Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing

LG Banaszak, V Giudice, X Zhao, Z Wu, S Gao… – Blood Cells, Molecules, and …, (2018) Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing… mutations. Library construction, exon capture, and sequencing was performed by Otogenetics (Atlanta, GA, USA) … described. 5-mC profiling, fragmentation, library preparation and sequencing were performed