Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis

Makishima H, Visconte V, Sakaguchi H, Jankowska AM, Abu Kar S, Jerez A, Przychodzen B, Bupathi M, Guinta K, Afable MG, Sekeres MA, Padgett RA, Tiu RV, Maciejewski JP. (2012) Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis. Blood. 119, 3203-3210 (Otogenetics Corporation performed both exome sequencing and RNA-seq for the study)